June 14, 2024

The regions of the brain involved in self-regulation of behavior are less active in adolescents predisposed to obesity, US researchers have found. This observation, which confirms that a large part of obesity results from behavior, should allow the development of new interventions to treat and prevent obesity, which affects more than 6% of young people aged 12 to 17 years. There stays the lorcaserin intermediate manufacturer factory there.

The researchers

The researchers made this observation when they subjected 36 New York City teens to functional magnetic resonance imaging (fMRI) which tells us about the level of activity in different areas of the brain while they were presented with words. Associated with fast food foods like “fries”, with healthy and low-fat foods like “Brussels sprouts”, and items unrelated to food.

  • Of these adolescents aged 14 to 19, 10 were overweight or obese, 16 were thin but considered to be at risk for obesity because their mothers were overweight or obese, and another 10 were thin and had little body risk of becoming obese because their mother was also thin. Participants were also asked to rate their appetite in response to each of these words. After this exam, a buffet including low-calorie and high-calorie foods was offered to all participants to see if their brain response matched their behavior in real life.

The Right Solutions

The researchers then noticed that the words associated with food induced an activation of the regions of the brain involved in emotions and the reward system in all subjects. It sort of means that “all teens see their reward system kicking in when they think of a nice pizza. In everyone, food stimulates the appetite.

In contrast, the brain structures responsible for attention and self-regulation were significantly less activated in especially overweight adolescents, and in those who were lean but predisposed to obesity due to their family history, to a lesser degree. , than in the thin ones with little risk of gaining weight and in which the activation was the highest. In addition, the behaviors of the various adolescents facing the buffet offered clearly reflected these latest results obtained by the MRI since the obese or overweight participants were those who ate the most, followed by those who, despite their thin waist, were at risk of becoming obese, while adolescents with small builds and no family predisposition were the ones who ate the least. From the lorcaserin hcl manufacturer  you can have the options now.


According to the researchers who conducted this study, this finding offers a new target to target in preventing and treating obesity, given that conventional interventions focused on diet and exercise are not very successful. “If we only do prevention through education by saying that French fries are not healthy because they contain a lot of fat, and that you need to exercise more, that won’t necessarily help you to adopt the right behavior. But by recognizing that self-regulation can make you act differently, you’ll know that you should avoid places where you can find French fries because you won’t be able to resist the urge to eat them due to your lack of self-regulation.